MD Pathology Residency Program
Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka.
Summative Examination Theory Papers with contents
(Applicable from the 2012-2013 session and onward)
The course duration is four years, divided into two phases: Phase A (two years) and Phase B (two years).
Each phase is composed of a number of basic three month block.
Course related allied specialties and basic science subjects are assessed by end block examination and are mentioned in the transcripts.
Summative assessments are taken on general and systemic pathology and pathology related branches.
The summative examinations are conducted by the university as Paper I, II, III, IV, V and VI examinations at the end of year 1, 2 and 4. Mark sheets mention the subjects with marks.
Total marks for each paper is 100. Pass marks is 60.
Summative examination papers with heading:
Paper I: General Pathology-1 (Cellular adaptation,Cell injury, inflammation, Tissue repair, haemodynamic dysorders)
Paper II: General Pathology-2 (Neoplasia, Infectious diseases, Nutritional Pathology, Developmental Pathology, Diseases of Aging, other sundry changes).
Paper III : Group A: Pathology Laboratory techniques
Group B: Molecular Pathology.
Paper IV: Group A: Medical Genetics
Group B: Basic Immunology and Immunological disorders
Paper V : Group A: Systemic Pathology
Group B: Systemic Pathology
Paper VI : Group C: Systemic Pathology
Group D: Cytopathology.
Question format:
For papers with A & B groups (e.g. Paper III to VI) each group (marks 50 for each group) will contain 8 short answer questions (SAQ, each carrying 5 marks) and one short essay questions (SEQ, each carrying 10 marks). There will be an alternate choice SEQ.
For papers without group (e.g. Paper I and II, total 16 short answer questions (SAQ, each carrying 5 marks) and 2 short essay questions (SEQ, each carrying 10 marks). There will be an alternate choice SEQ.
CONTENTS OF PAPERS
PAPER I (Total marks 100, Pass marks 60) TITLE: General Pathology - 1 CONTENTS:
i. Cellular adaptation, Cell injury and Cell death
ii. Acute and chronic inflammation
iii. Tissue repair
iv. Haemodynamic disorders
v. other sundry changes
PAPER II (Total marks 100, Pass marks 60) TITLE: General Pathology - 2
CONTENTS:
1. Neoplasia
2. Infectious diseases
3. Nutritional Pathology
4. Developmental Pathology
5. Diseases of Aging
PAPER III (Total marks 100, Gr. A-50, Gr. B-50, Pass marks 60 in aggregate)
TITLE: Pathology laboratory techniques and Molecular Pathology
GR. A TITLE: Pathology laboratory techniques CONTENTS:
a. Organization of a histopathology/ cytopathology laboratory
b. Management of a laboratory- documentation, preservation, information storage (record keeping), laboratory safety and discarding of specimen
c. Microscopy-general, fluorescence and electron microscopy
d. Fixatives-mechanism of action, classification, choice of a fixative
e. Microtomy - general principle, microtome knives, abrasives
f. Principles of grossing
g. Routine tissue processing
h. Principles of staining - routine and special stains
i. Frozen section
j. Cytology laboratory techniques- basic sampling techniques, processing and staining
k. Histopathology and cytopathology report principals.
l. Immunohistochemistry
m. Immunofluorescence
n. Mounting and display of museum specimen
GR. B TITLE: Molecular Pathology
CONTENTS:
1. Basic Molecular Cell Biology
DNA and Chromosomal Structure and Function
Cytogenetics
Basic cytogenetic techniques
molecular cytogenetic techniques
cytogenetics in research
Regulation of transcription
Intracellular compartments and protein sorting
Cell cycle and cell death
Intracellular signalling
Gene Analysis
Restriction enzyme analysis
DNA sequencing
Cloning
Tissue Handling:
Biobanking, Tissue bank
Tissue microarray construction and applications
2. Genomic Technologies
Introduction to array technology
RNAi technology
Introduction to proteomics
3. Molecular Diagnostics
Molecular diagnostics, basic concepts.
Molecular diagnosis of Infection
Molecular diagnosis of cancer
Molecular diagnostics in immunology and genetics
4. Molecular Pathology of Solid Tumours
Molecular genetics of Cancer
Familial cancer syndromes.
Colorectal cancer as a model of multistep malignancy
Breast cancer: emerging molecular classification
Microbial carcinogenesis 1
5. Molecular Cytogenetics of Tumour:
Chromosomes abnormalities in haematological malignancies.
CML
myeloid leukaemias
acute lymphoblastic leukaemias
cronic lymphoproliferative disorders and lymphomas.
Solid tumour cytogenetics
6. Computational Genomics, basic concepts.
PAPER IV TITLE: Medical genetics and Immunology (Total marks 100, Gr. A-50, Gr. B-50, Pass marks 60 in aggregate) GR. A TITLE: Medical genetics
CONTENTS:
· Cytogenetic disorders.
· Diseases due to single gene defect.
· Multifactorial disorders.
· Diagnosis of genetic diseases
· Treatment of genetic diseased
· Genetic counseling
GR. B TITLE: Basic Immunology and Immunological disorders
CONTENTS:
Basic immunology:
· Organization and cells of immune system.
· Immunity and its types. Immunoglobulins, antibody, antigen reorganization
· Complement system.
Immunological disorders:
· Mechanisms of tissue damage in immunological disorders.
· Hypersensitivity reactions.
· Immunological tolerance.
· Autoimmune diseases.
· Immunodeficiency states.
· MHC system. HLA and disease association.
· Organ transplant.
· Transfusion reactions.
· Diagnostic immunology.
PAPER V (Total marks 100, Gr. A-50, Gr. B-50, Pass marks 60 in aggregate) TITLE: Systemic Pathology
Group A
CONTENTS: Diseases of the
1. Cardiovascular system,
2. Respiratory system,
3. Gastrointestinal system, Liver and biliary tract, Pancreas
4. Head and neck,
5. Eye, ear, nose and paranasal sinus.
Group B
1. Haematopoietic and lymphoid tissue
2. Musculoskeletal system
3. Soft tissue
4. Nervous system
PAPER VI
(Total marks 100, Gr. A-50, Gr. B-50, Pass marks 60 in aggregate)
Group C
TITLE: Systemic Pathology
1. Male and female genital system,
2. Breast
3. Kidney and urinary tract
4. Endocrine system
5. Skin,
Group D
TITLE: Cytopathology
1. Structure of mammalian cells, benign pathological processes affecting the cell, characteristic of a malignant cell, effusion fluids
2. Cytology of the female genital tract, respiratory tract, oral cavity, urinary tract and prostate, breast and nipple, gastrointestinal tract, CSF and other body fluids